Carla M A Pinto
Polytechnic of Porto, Portugal
Title: Persistence of low levels of plasma viremia and of the latent reservoir in patients under ART: A fractional order approach
Biography
Biography: Carla M A Pinto
Abstract
Low levels of viral load are found in HIV infected patients, after many years under successful suppressive anti-retroviral therapy (ART). The factors leading to this persistence are still under debate but it is now more or less accepted that the latent reservoir may be crucial to the maintenance of this residual viremia. In this talk, we focus on the role of the latent reservoir in the persistence of the latent reservoir and of the plasma viremia in a fractional order (FO) model for HIV infection. The proposed model provides new insights on the role of the latent reservoir in the persistence of the latent reservoir and of the plasma virus. To our best knowledge, this is the first FO model that deals with the role of the latent reservoir in the persistence of low levels of viremia and of the latent reservoir.
